Steelers vs Patriots Prediction, Picks & Odds | 21 Sep 2025

NFL Betting Preview: Steelers vs Patriots

The Pittsburgh Steelers clash with the New England Patriots in this NFL Week 3 matchup at Gillette Stadium, with kickoff scheduled for 01:00 on Monday 22 September. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

Can Patriots Gain the Upper Hand?

Our betting prediction is that there will be home-field advantage when the Patriots face the Steelers. You can currently get 2.02 about this happening which look like great odds.

Backing Patriots to come through? Be sure to grab the exclusive Stake promo code and check out our sportsbook review before placing your bet.

Patriots Won Previous H2H Clash

Pittsburgh Steelers were beaten 31-17 at Acrisure Stadium in their previous game, being turned over at home to Seattle Seahawks. The Steelers finished with 267 total yards, made up of 195 through the air and 72 on the ground. They produced 13 first downs and scored a touchdown through the air.

New England Patriots triumphed in their last game. It was on the road where Miami Dolphins were beaten 33-27 at Hard Rock Stadium. The Patriots put up 333 yards, including 211 passing and 122 rushing yards. The offense picked up 18 first downs and crossed the goal line 4 times.

Head-to-Head Statistics

The Patriots had the edge in the most recent matchup between these teams. At Acrisure Stadium, they recorded a 21-18 win over the Steelers. The Patriots have a 100% win record when it comes to the previous 3 H2H meetings.

Quarterbacks

Aaron Rodgers

Drake Maye

Steelers vs Patriots Prediction & Picks

Discover the top Steelers vs Patriots betting angles — from our trusted match prediction and likely score to the best prop plays and a customized bet builder.

Game Prediction

We can’t resist going for the Patriots on the Moneyline, with our pick made with confidence and there is 2.02 available that they win this NFL matchup.

Our NFL predictions are built after tracking the latest team news and reviewing recent form. We also dive into up-to-date stats, which often serve as a solid barometer for how the action might unfold.

Key Steelers vs Patriots stats:

• Steelers have lost 4 of their last 5 games.
• Steelers have lost 7 of their last 10 games.
• Patriots have won the last 3 games between these teams.

Patriots Moneyline Probability

According to the latest betting odds, our pick has a 49.5% chance of winning. Our cappers think there’s a stronger chance of success and calculate the probability to be 55-60%. This is why we can recommend this bet.

If you’re looking for greater odds, the Patriots can be backed at a bigger price against the spread. Also consider the option of looking at the Result & Total and Double Result lines.

Before your next bet, explore our betting offers guide filled with top bonuses, the latest promotions, and free bet deals.

Best Bet

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Player Prop Picks

Correct Score Prediction

Steelers 20 - 28 Patriots

The Patriots will be chasing down a victory and a winning scoreline of 28-20 might be along the right lines. There are enormous odds available about this bet.

Steelers vs Patriots Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Tight Affair Likely According to the Books

When you consider the latest Moneyline odds, you can find New England Patriots at 1.98 whereas Pittsburgh Steelers are 1.86. The leading sportsbooks give the hosts a 51% chance of success.

1.5 is the spread and 44.5 is the total points line. A bet on the Totals allows fans to use the latest NFL data to good effect. Those expecting a low total can back Under 44.5 at 1.88.

Every matchup offers a deep selection of team props and game lines and the top NFL betting sites deliver excellent pre-game and in-game wagering opportunities. It’s all about finding the bets that match your game plan.

Jaylen Warren Favorite to Be First Touchdown Scorer

Those interested in favorite Jaylen Warren to score the first touchdown are able to get 6.50. If the Anytime TD angle makes appeal, then this is 1.95.

Touchdown

Receiving Yards

Rushing Yards

Passing Yards

Micro Betting

Among the various options for wagering on the NFL, you will find that micro betting is provided. It focuses on short-term in-game outcomes such as whether a touchdown will be scored within the next 10 minutes.

Patriots Have Suffered Eight Losses in Past Ten at Home

The Patriots own a 2-8 mark in their past 10 home games, putting up 16.80 points on average and giving up 24.70.

The Steelers own a 5-5 mark in their past 10 games on the road, putting up 23.80 points on average and giving up 25.60.

The last Gillette Stadium meeting saw the Patriots beat the Steelers 33-3.

Last 10 Games		W-L	P	PF	PA	O44.5	U44.5
Patriots Home Stats		2-8	41.50	16.80	24.70	5	5
Steelers Away Stats		5-5	49.40	23.80	25.60	6	4

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O44.5 = Games Over 44.5 Points
• U44.5 = Games Under 44.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Pittsburgh Steelers Stats

New England Patriots Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 home games

Point Spread

• -1.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -1.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• +1.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +1.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

• Game Totals: An average of 48.80 pts in the previous 10 games
• Game Totals on the Road: An average of 49.40 pts in the previous 10 games on the road
• Over 44.5: Covered in 4 of the previous 10 games
• Over 44.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 21.20 pts and allowed 27.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 23.80 pts and allowed 25.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 44.10 pts in the previous 10 games
• Game Totals at Home: An average of 41.50 pts in the previous 10 home games
• Over 44.5: Covered in 7 of the previous 10 games
• Over 44.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 19.40 pts and allowed 24.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 16.80 pts and allowed 24.70 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 300.80 Yds. Allowed 375.40 Yds
• Rushing Yards: Gained 95.30 Yds. Allowed 136.80 Yds
• Passing Yards: Gained 205.50 Yds. Allowed 238.60 Yds
• Total Touchdowns: Scored 2.30 TD. Allowed 3.40 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 1.20 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.90 TD
• Total 1st Downs: Picked up 17.10. Allowed 22.70
• Total Turnovers: Committed 1.10. Committed by opponents 1.70
• Total Penalties: Committed 5.10. Committed by opponents 6.40
• Penalty Yards: Lost 41.90 Yds. Gained 50.70 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 325.00 Yds. Allowed 332.30 Yds
• Rushing Yards: Gained 115.20 Yds. Allowed 111.80 Yds
• Passing Yards: Gained 209.80 Yds. Allowed 220.50 Yds
• Total Touchdowns: Scored 2.00 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.80 TD
• Total 1st Downs: Picked up 19.00. Allowed 19.50
• Total Turnovers: Committed 1.30. Committed by opponents 0.60
• Total Penalties: Committed 7.50. Committed by opponents 6.50
• Penalty Yards: Lost 59.10 Yds. Gained 47.10 Yds

Last 10 Games on the Road

• Total Yards: Gained 317.70 Yds. Allowed 352.60 Yds
• Rushing Yards: Gained 107.10 Yds. Allowed 132.40 Yds
• Passing Yards: Gained 210.60 Yds. Allowed 220.20 Yds
• Total Touchdowns: Scored 2.70 TD. Allowed 3.10 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 1.50 TD
• Passing Touchdowns: Scored 1.70 TD. Allowed 1.40 TD
• Total 1st Downs: Picked up 18.20. Allowed 21.50
• Total Turnovers: Committed 0.90. Committed by opponents 1.60
• Total Penalties: Committed 6.40. Committed by opponents 6.00
• Penalty Yards: Lost 52.80 Yds. Gained 54.60 Yds

Last 10 Home Games

• Total Yards: Gained 289.60 Yds. Allowed 341.90 Yds
• Rushing Yards: Gained 117.50 Yds. Allowed 131.20 Yds
• Passing Yards: Gained 172.10 Yds. Allowed 210.70 Yds
• Total Touchdowns: Scored 1.70 TD. Allowed 2.70 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.00 TD. Allowed 1.70 TD
• Total 1st Downs: Picked up 17.30. Allowed 20.20
• Total Turnovers: Committed 1.20. Committed by opponents 0.80
• Total Penalties: Committed 7.00. Committed by opponents 5.50
• Penalty Yards: Lost 60.40 Yds. Gained 45.30 Yds

Team News

NFL Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Division Conference League

AFC East	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Bills	3	0	0	1.000	102	71	31	2-0-0	1-0-0	2-0-0	3-0-0	3-0-0	3W
Patriots	1	2	0	0.333	60	68	-8	0-2-0	1-0-0	1-0-0	1-2-0	1-2-0	1L
Dolphins	0	3	0	0.000	56	97	-41	0-1-0	0-2-0	0-2-0	0-3-0	0-3-0	3L
Jets	0	3	0	0.000	69	93	-24	0-2-0	0-1-0	0-1-0	0-2-0	0-3-0	3L

AFC North	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Bengals	2	1	0	0.667	58	91	-33	1-0-0	1-1-0	1-0-0	2-0-0	2-1-0	1L
Steelers	2	1	0	0.667	72	77	-5	0-1-0	2-0-0	0-0-0	2-0-0	2-1-0	1W
Ravens	1	1	0	0.500	81	58	23	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1W
Browns	1	2	0	0.333	46	68	-22	1-1-0	0-1-0	0-2-0	0-2-0	1-2-0	1W

AFC South	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Colts	3	0	0	1.000	103	56	47	2-0-0	1-0-0	1-0-0	3-0-0	3-0-0	3W
Jaguars	2	1	0	0.667	70	51	19	2-0-0	0-1-0	1-0-0	1-1-0	2-1-0	1W
Texans	0	3	0	0.000	38	51	-13	0-1-0	0-2-0	0-1-0	0-1-0	0-3-0	3L
Titans	0	3	0	0.000	51	94	-43	0-2-0	0-1-0	0-1-0	0-2-0	0-3-0	3L

AFC West	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Chargers	3	0	0	1.000	70	50	20	2-0-0	1-0-0	3-0-0	3-0-0	3-0-0	3W
Chiefs	1	2	0	0.333	60	56	4	0-1-0	1-1-0	0-1-0	0-1-0	1-2-0	1W
Raiders	1	2	0	0.333	53	74	-21	0-1-0	1-1-0	0-1-0	1-1-0	1-2-0	2L
Broncos	1	2	0	0.333	68	64	4	1-0-0	0-2-0	0-1-0	1-2-0	1-2-0	2L

NFC East	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Eagles	3	0	0	1.000	77	63	14	2-0-0	1-0-0	1-0-0	2-0-0	3-0-0	3W
Commanders	2	1	0	0.667	80	57	23	2-0-0	0-1-0	1-0-0	1-1-0	2-1-0	1W
Cowboys	1	2	0	0.333	74	92	-18	1-0-0	0-2-0	1-1-0	1-2-0	1-2-0	1L
Giants	0	3	0	0.000	52	83	-31	0-1-0	0-2-0	0-2-0	0-2-0	0-3-0	3L

NFC North	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Packers	2	1	0	0.667	64	44	20	2-0-0	0-1-0	1-0-0	2-0-0	2-1-0	1L
Vikings	2	1	0	0.667	81	56	25	1-1-0	1-0-0	1-0-0	1-1-0	2-1-0	1W
Lions	1	1	0	0.500	65	48	17	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Bears	1	2	0	0.333	76	93	-17	1-1-0	0-1-0	0-2-0	1-2-0	1-2-0	1W

NFC South	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Buccaneers	3	0	0	1.000	72	66	6	1-0-0	2-0-0	1-0-0	1-0-0	3-0-0	3W
Falcons	1	2	0	0.333	42	59	-17	0-1-0	1-1-0	0-2-0	1-2-0	1-2-0	1L
Panthers	1	2	0	0.333	62	53	9	1-0-0	0-2-0	1-0-0	1-1-0	1-2-0	1W
Saints	0	3	0	0.000	47	90	-43	0-2-0	0-1-0	0-0-0	0-3-0	0-3-0	3L

NFC West	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
49ers	3	0	0	1.000	59	49	10	1-0-0	2-0-0	2-0-0	3-0-0	3-0-0	3W
Cardinals	2	1	0	0.667	62	51	11	1-0-0	1-1-0	0-1-0	2-1-0	2-1-0	1L
Seahawks	2	1	0	0.667	88	47	41	1-1-0	1-0-0	0-1-0	1-1-0	2-1-0	2W
Rams	2	1	0	0.667	73	61	12	1-0-0	1-1-0	0-0-0	0-1-0	2-1-0	1L

AFC Conference	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Bills	3	0	0	1.000	102	71	31	2-0-0	1-0-0	2-0-0	3-0-0	3-0-0	3W
Chargers	3	0	0	1.000	70	50	20	2-0-0	1-0-0	3-0-0	3-0-0	3-0-0	3W
Bengals	2	1	0	0.667	58	91	-33	1-0-0	1-1-0	1-0-0	2-0-0	2-1-0	1L
Colts	3	0	0	1.000	103	56	47	2-0-0	1-0-0	1-0-0	3-0-0	3-0-0	3W
Raiders	1	2	0	0.333	53	74	-21	0-1-0	1-1-0	0-1-0	1-1-0	1-2-0	2L
Patriots	1	2	0	0.333	60	68	-8	0-2-0	1-0-0	1-0-0	1-2-0	1-2-0	1L
Ravens	1	1	0	0.500	81	58	23	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1W
Steelers	2	1	0	0.667	72	77	-5	0-1-0	2-0-0	0-0-0	2-0-0	2-1-0	1W
Broncos	1	2	0	0.333	68	64	4	1-0-0	0-2-0	0-1-0	1-2-0	1-2-0	2L
Jaguars	2	1	0	0.667	70	51	19	2-0-0	0-1-0	1-0-0	1-1-0	2-1-0	1W
Titans	0	3	0	0.000	51	94	-43	0-2-0	0-1-0	0-1-0	0-2-0	0-3-0	3L
Chiefs	1	2	0	0.333	60	56	4	0-1-0	1-1-0	0-1-0	0-1-0	1-2-0	1W
Jets	0	3	0	0.000	69	93	-24	0-2-0	0-1-0	0-1-0	0-2-0	0-3-0	3L
Browns	1	2	0	0.333	46	68	-22	1-1-0	0-1-0	0-2-0	0-2-0	1-2-0	1W
Texans	0	3	0	0.000	38	51	-13	0-1-0	0-2-0	0-1-0	0-1-0	0-3-0	3L
Dolphins	0	3	0	0.000	56	97	-41	0-1-0	0-2-0	0-2-0	0-3-0	0-3-0	3L

NFC Conference	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Eagles	3	0	0	1.000	77	63	14	2-0-0	1-0-0	1-0-0	2-0-0	3-0-0	3W
Buccaneers	3	0	0	1.000	72	66	6	1-0-0	2-0-0	1-0-0	1-0-0	3-0-0	3W
Packers	2	1	0	0.667	64	44	20	2-0-0	0-1-0	1-0-0	2-0-0	2-1-0	1L
49ers	3	0	0	1.000	59	49	10	1-0-0	2-0-0	2-0-0	3-0-0	3-0-0	3W
Cardinals	2	1	0	0.667	62	51	11	1-0-0	1-1-0	0-1-0	2-1-0	2-1-0	1L
Rams	2	1	0	0.667	73	61	12	1-0-0	1-1-0	0-0-0	0-1-0	2-1-0	1L
Falcons	1	2	0	0.333	42	59	-17	0-1-0	1-1-0	0-2-0	1-2-0	1-2-0	1L
Seahawks	2	1	0	0.667	88	47	41	1-1-0	1-0-0	0-1-0	1-1-0	2-1-0	2W
Commanders	2	1	0	0.667	80	57	23	2-0-0	0-1-0	1-0-0	1-1-0	2-1-0	1W
Vikings	2	1	0	0.667	81	56	25	1-1-0	1-0-0	1-0-0	1-1-0	2-1-0	1W
Cowboys	1	2	0	0.333	74	92	-18	1-0-0	0-2-0	1-1-0	1-2-0	1-2-0	1L
Lions	1	1	0	0.500	65	48	17	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Panthers	1	2	0	0.333	62	53	9	1-0-0	0-2-0	1-0-0	1-1-0	1-2-0	1W
Bears	1	2	0	0.333	76	93	-17	1-1-0	0-1-0	0-2-0	1-2-0	1-2-0	1W
Saints	0	3	0	0.000	47	90	-43	0-2-0	0-1-0	0-0-0	0-3-0	0-3-0	3L
Giants	0	3	0	0.000	52	83	-31	0-1-0	0-2-0	0-2-0	0-2-0	0-3-0	3L

NFL Team	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Bills	3	0	0	1.000	102	71	31	2-0-0	1-0-0	2-0-0	3-0-0	3-0-0	3W
Colts	3	0	0	1.000	103	56	47	2-0-0	1-0-0	1-0-0	3-0-0	3-0-0	3W
Chargers	3	0	0	1.000	70	50	20	2-0-0	1-0-0	3-0-0	3-0-0	3-0-0	3W
Eagles	3	0	0	1.000	77	63	14	2-0-0	1-0-0	1-0-0	2-0-0	3-0-0	3W
49ers	3	0	0	1.000	59	49	10	1-0-0	2-0-0	2-0-0	3-0-0	3-0-0	3W
Buccaneers	3	0	0	1.000	72	66	6	1-0-0	2-0-0	1-0-0	1-0-0	3-0-0	3W
Cardinals	2	1	0	0.667	62	51	11	1-0-0	1-1-0	0-1-0	2-1-0	2-1-0	1L
Bengals	2	1	0	0.667	58	91	-33	1-0-0	1-1-0	1-0-0	2-0-0	2-1-0	1L
Packers	2	1	0	0.667	64	44	20	2-0-0	0-1-0	1-0-0	2-0-0	2-1-0	1L
Jaguars	2	1	0	0.667	70	51	19	2-0-0	0-1-0	1-0-0	1-1-0	2-1-0	1W
Rams	2	1	0	0.667	73	61	12	1-0-0	1-1-0	0-0-0	0-1-0	2-1-0	1L
Vikings	2	1	0	0.667	81	56	25	1-1-0	1-0-0	1-0-0	1-1-0	2-1-0	1W
Steelers	2	1	0	0.667	72	77	-5	0-1-0	2-0-0	0-0-0	2-0-0	2-1-0	1W
Seahawks	2	1	0	0.667	88	47	41	1-1-0	1-0-0	0-1-0	1-1-0	2-1-0	2W
Commanders	2	1	0	0.667	80	57	23	2-0-0	0-1-0	1-0-0	1-1-0	2-1-0	1W
Ravens	1	1	0	0.500	81	58	23	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1W
Lions	1	1	0	0.500	65	48	17	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Falcons	1	2	0	0.333	42	59	-17	0-1-0	1-1-0	0-2-0	1-2-0	1-2-0	1L
Panthers	1	2	0	0.333	62	53	9	1-0-0	0-2-0	1-0-0	1-1-0	1-2-0	1W
Bears	1	2	0	0.333	76	93	-17	1-1-0	0-1-0	0-2-0	1-2-0	1-2-0	1W
Browns	1	2	0	0.333	46	68	-22	1-1-0	0-1-0	0-2-0	0-2-0	1-2-0	1W
Cowboys	1	2	0	0.333	74	92	-18	1-0-0	0-2-0	1-1-0	1-2-0	1-2-0	1L
Broncos	1	2	0	0.333	68	64	4	1-0-0	0-2-0	0-1-0	1-2-0	1-2-0	2L
Chiefs	1	2	0	0.333	60	56	4	0-1-0	1-1-0	0-1-0	0-1-0	1-2-0	1W
Raiders	1	2	0	0.333	53	74	-21	0-1-0	1-1-0	0-1-0	1-1-0	1-2-0	2L
Patriots	1	2	0	0.333	60	68	-8	0-2-0	1-0-0	1-0-0	1-2-0	1-2-0	1L
Texans	0	3	0	0.000	38	51	-13	0-1-0	0-2-0	0-1-0	0-1-0	0-3-0	3L
Dolphins	0	3	0	0.000	56	97	-41	0-1-0	0-2-0	0-2-0	0-3-0	0-3-0	3L
Saints	0	3	0	0.000	47	90	-43	0-2-0	0-1-0	0-0-0	0-3-0	0-3-0	3L
Giants	0	3	0	0.000	52	83	-31	0-1-0	0-2-0	0-2-0	0-2-0	0-3-0	3L
Jets	0	3	0	0.000	69	93	-24	0-2-0	0-1-0	0-1-0	0-2-0	0-3-0	3L
Titans	0	3	0	0.000	51	94	-43	0-2-0	0-1-0	0-1-0	0-2-0	0-3-0	3L